Post Traumatic Stress Disorder

topic posted Mon, November 19, 2007 - 5:05 PM by 
We already know that traumatic experiences can lead to certain forms of brain damage. The BIG question here is if there are no-invasive methods capable of reversing said damage.

www.emdr.com/briefdes.htm

It stands to reason that if something can be done, it can also be undone. In the case of neurological damage and compromised cognition, this particular form of therapy suggests that neural responses can be effectively re-wired without the use of invasive practices. It's really nothing more than re-conditioning the immediate response. Over time this method can and will re-condition the individual's perception, with the added benefit of re-conditioning the immediate response.

-K
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  • Re: Post Traumatic Stress Disorder

    Mon, November 19, 2007 - 8:58 PM
    Eye movement, eh? The reductionist in me wants to know the underlying neurochemical processes involved... I don't doubt that it might work on principle, as many activities can create neurological effects through complex causal chains. But any positing of causal links from activity at the conceptual & sensory levels of cognition to the neurological level needs a lot of repeatable evidence to show not just that there "is* a link (somewhere, somehow, indirectly), but *how* that link works; otherwise it might as well just be waving a dead chicken over someone while also accidentally, unawares, doing something else that actually does the work. (Yes, I just compared psychologists to witch doctors.)

    There seems to be a fair number of studies referenced ( www.emdr.com/refs.htm ) but there's a lot of stuff in psychologist-peer-reviewed journals that seems to boil down to, well, we tried this and a bunch of other psychologists tried it too, and it seems to work pretty well, in fact it works in an overwhelming number of cases, so we're gonna keep using it, but we don't have much idea of *how* it works in the brain.

    I'd really like to know *how* it works, at the physical-neurological level. Maybe it's just me, but that tends to inspire more confidence in me. (I'm kinda slow; I need to see the A->B->C->D. I tend to be one of those people who get distracted by continuity mistakes in movies... ...wait a minute how did his clothes suddenly get dry?, etc.)


    I saw a video not long ago of a talk at McGill U. in which the lecturer outlined some research into reconditioning the response to the memories which triggered PTSD. Apparently there are proteins produced in the amygdala which help to 'encode" or lock into place the association of the memory in question with the strong emotional response. This association gets reformed each time the memory is recalled. But if protein-formation inhibitory drugs are given at the time that the person is recalling the triggering memory (it seems they can target the amygdala's process that specifically), the proteins are not formed that time and the association is not re-encoded, thus breaking the cycle. The person can then recall the memory after that without having a PTSD episode.

    (It was late night when I saw this, and the details are a bit foggy, but that's the gist of what I recall.)
    • Re: Post Traumatic Stress Disorder

      Mon, November 19, 2007 - 9:34 PM
      I recently sat through a lecture on neuroscience and psychotherapy and the lecturer touched on EMDR. The way I understood it is that normally, emotional memory is processed from the amydgala through the hippocampus and into the cortex. The processing through the hippocampus normally takes place during REM sleep, but in the case of PTSD, the memory becomes "stuck" in the amydgala. EMDR helps "unstick" the memory and process it through the hippocampus the way it normally would be during REM sleep.

      Obviously that's a layman's description and I don't know if it's pure hypothesis or if there's some evidence to back it up, but there it is.

      > but we don't have much idea of *how* it works in the brain.

      Isn't that the case more often than not?
    • Re: Post Traumatic Stress Disorder

      Tue, November 20, 2007 - 1:03 AM
      Hi Kai

      I have some sympathy.... was talking about this with a colleague last night. The EMDR practitioners' explanations are invariably metaphorical or expressed in similes... but I don't see how it can be any other way with our current state of neurological knowledge. We are still a long way off adequate descriptions of complex processes.

      There is an argument that EMDR is no more effective in treating trauma than desensitisation, having the client stay with the trauma until the distress diminishes. It is, however, in my experience a damn site faster and works on a number of other levels (I have used it to help one guy erase an unwanted fetish response for example).

      <irony>Hell Kai, if we waited for an adequate reductionist explanation, we would still be trapanning and applying electrical currents across people's temporal lobes </irony>
      • Re: Post Traumatic Stress Disorder

        Tue, November 20, 2007 - 2:47 PM
        An explanation is one thing. Having empirical evidence that a method actually works is another. In the case of EMDR I believe that there is no real evidence that the procedure is effective beyond the exposure therapy it is used in conjunction with.
        • Re: Post Traumatic Stress Disorder

          Tue, November 20, 2007 - 4:19 PM
          other than the speed... one of the reasons it is recommended by NICE (National Institute of Clinical Excellence) in the UK as a treatment for PTSD
          • Re: Post Traumatic Stress Disorder

            Tue, November 20, 2007 - 4:52 PM
            Tali - Speed? Weird! Do you have any links or anything explaining how it's meant to work or the effects? Seems like speed would heighten anxiety and paranoia on first consideration. Very interesting.
            • Re: Post Traumatic Stress Disorder

              Wed, November 21, 2007 - 7:37 AM
              There is nothing in the EMDR process that should evoke persecutory belief systems, but by speed I was referring to the rapidity with results can be achieved. The thing with EMDR is that results can be very quick... this is going to be one of it's appeals to the NICE, since within a National health Service such as that in the UK, efficacy is not the only deciding factor as to whether a treatment will be recommended... it will include economic issues as well. So brief therapies are all the rage :-)

              The EMDR process DOES require that the client attends to their distress and the images associated with trauma, but with sensitive management that should not provoke heightened anxiety.
              • Re: Post Traumatic Stress Disorder

                Wed, November 21, 2007 - 8:16 AM
                Tali - "The EMDR process DOES require that the client attends to their distress and the images associated with trauma, but with sensitive management that should not provoke heightened anxiety."

                Yes, I understand that, that's why I said that there's a cognitive component (which *may* make the "tapping" part just sort of window dressing, or more a form of distraction or a calming ritual). Having a ritual or repeated action that one uses when anxious is very soothing (in very simplistic terms this is sort of what obsessive compulsion is, when this mechanism has gone haywire). I'd suspect it has to do with the soothing effect of a mother's heartbeat - we like repetition, it makes us feel safe :-) It's very similar to the process of desensitization via visiting the site of trauma (though it's revisiting the memory). Also, just reliving trauma in a therapeutic setting with a caring therapist helps recontextualize trauma as well, and provide new insight in a safe environment for the patient. I've never tried it myself - I find deep breathing and just being in the moment and conscious works well for me (skills I develop using meditation). I've had some people tell me it's worked for them, and others that it hasn't. I'm not saying it doesn't work - clearly it does for some people - just that it may work for reasons that have nothing or little to do with the specifics of the actual method. Of course, it may also work because of the specifics of the method. Until it's been proven one way or the other, we just don't know :-)
              • Re: Post Traumatic Stress Disorder

                Wed, November 21, 2007 - 9:25 AM
                Tali - *lol* I thought when you said "speed" initially that you meant amphetamines not rapidity. Hence my surprise and mentioning increasing paranoia. I just realized that my misunderstanding may not have been clear to you and may be leading to further misunderstandings :-)
  • Re: Post Traumatic Stress Disorder

    Tue, November 20, 2007 - 3:19 PM
    Glad it's working for you Kryssa :-) At the end of the day, if something is working for us that's the most important thing to us personally.

    That said, so far there aren't really any invasive methods that have been proven to reverse PTSD that I know of (though, of course, there's plenty I don't know :-). The most common treatments used for PTSD are behavioral, including exposure treatments which aim to desensitize the person to the traumatic experience so the situation/place/activity slowly becomes normalized (in the case of work accidents, people who have been attacked, and such). There was a drug recently developed that is being considered as a treatment for PTSD but it's still all pretty theoretical, and there's a lot of ethical debate around "erasing" memories (and lots and lots of potential side effects that are quite undesirable).

    PTSD is a pretty trendy diagnosis at the moment, I'd suspect some people being diagnosed with it have other anxiety disorders or conditions that are being misdiagnosed. (I'm not at all suggesting this is the case with you! Just that it's likely since this is what happens when a certain diagnosis is kinda trendy or a particular treatment is being strongly promoted.) Kinda like how everyone who has trouble concentrating is designated "ADD" these days, when quite often there are dietary and behavioral issues that are really the culprit for an inability to concentrate.

    Kryssa - "It stands to reason that if something can be done, it can also be undone."

    Not really, I don't mean to be an ass but it's just not a logical assumption based in physical reality. For instance, once a nuclear bomb has exploded it can't be "undone". It also doesn't really hold true when speaking about human biology. Sure many things can be healed, but many can't. And healing isn't the same as "undoing". The saying "you can't unring a bell" exists for a reason :-)

    All that said, I'm glad this is working for you for whatever reason - because it serves as a form of cognitive therapy that makes you slow down and manage your thoughts, is a placebo (hey, if a placebo works all the better! :-), or has an actual physiological basis (much in the same way snapping a band on one's wrist can work as aversion therapy). It will be interesting to see what is revealed when EMDR is eventually studied in a context that shows what's going on neurobiologically :-)
    • Re: Post Traumatic Stress Disorder

      Tue, November 20, 2007 - 8:04 PM
      "and there's a lot of ethical debate around "erasing" memories (and lots and lots of potential side effects that are quite undesirable)."

      One of the points in the McGill lecture was that the drugs could leave the non-amygdala-located aspects of the memory intact while preventing the reformation of the proteins produced in the amygdala which encode the strong emotional content. He started the lecture with a reference to "The Eternal Sunshine of the Spotless MInd" as a way to set up the later point that this potential therapy would differ from the complete wipe that occurs for the Jim Carrey character in that film.

      My oomments earlier weren't meant as a hard-ass reductionist stance, more as an expression of frustration at the "poking around in the dark" (or at least a dim room) state of such psychological experimentation, with the hope that psychologists won't neglect the psychiatric goal of correlating recently gained knowledge about neurochemistry with these perceptual level manipulations which appear to have some empirical validity.

      From my own recent experience, ironically enough, I can attest to the semi-witch-doctory state of current psychiatric drug therapies - i.e., they seem to accomplish their stated goals, but the side effects show how crudely aimed they still are. (So the "it seems to work, but we don't know exactly how yet" criticism applies just as much to neurochemical research and application.) Late last spring, after several months in the grip of a bout of debiliating depression that the usual counseling wasn't helping enough I finally decided to see about going on anti-depressants, something I had resisted for a long time. So I started on Celexa, was on that for 3 months, it reduced the mood extremes, sure enough, but introduced other unpleasantries like insomnia (which soon increased my anxiety, of course). switched to Zoloft, which let me sleep, but introduced recurrent nausea, among other things. So while they both kept me functioning better than I would have (based on my my past experiences with untreated depressive episodes, which I've recognized in hindsight, with outside help), and allowed me to process the events which had triggered the depressive plunge, get perspective, etc., the cost was too high in the long run. I stopped in early October and the return of my full emotional range, minus the darker depths and manic highs (because I'd methodically removed the triggers of the last episode from my life), was remarkable. (I emerged from my Zombie Summer, to exaggerate a bit.) I side with Brooke Shields over Scientology Poster Boy on the question of whether drugs should be used at all. (If you remember, Mr. Cruise Missile suggested that vitamins were enough. Twerp.) The drugs had some limited usefulness, not nil, and I don't regret having tried them, but a preventative and more holistic approach to depression remains a better long-term option until such time as neurochemical precision is achieved.

      So anyway, sure; whatever works, eye movement, drugs, people need something *now* that works at least to some degree, but I don't want to lose sight of the goal of such precise therapies.
      • Re: Post Traumatic Stress Disorder

        Wed, November 21, 2007 - 5:09 AM
        Kai - Well, it's pretty much a given that any drug that works will also have side effects. That probably won't change, perhaps ever, and will vary from patient to patient and so on even as drugs get more elegant and precise. Aspirin has side effects. Hell, even food has "side effects". Drugs have effects, the undesirable ones are called "side effects". This may change but it's unlikely. The battle here is really with the pharmaceutical companies that release poorly tested drugs (or ignore and don't inform doctors about side effects - they make enough of the drugs that even the massive payouts such as that recently over Vioxx doesn't deter this kind of thing).

        Sure there are generally better ways to treat depression than drugs, and certainly no responsible doctor *only* treats with drugs. In the US insurance companies don't want to pay for talk therapies because they take time so cost more money, so you end up with lots of people on drugs as a sort of band-aid. That said, if someone's in a very deep depression then sometimes drugs can help give them the energy to start the process (though if the patient is suicidal it's important to make sure it doesn't just give them the energy to kill them self). There's also the question of patient willingness and ability to actually take the non-pharmaceutical steps to manage their depression - such as getting daily exercise and eating properly. There's also the issue of GPs with no training as therapist diagnosing and treating depression when they're not really trained to do so, and prescribing drugs but not insisting upon talk therapy as well.

        Sure prevention is best but when people don't know or can't take care of themselves then doctors and therapists have to deal with the state they're in by the time they eventually come for help. Heh, and on the up side the side effects can serve as a good motivator for people to make the lifestyle changes and be consistent in applying them so as to prevent another bout of depression, as they seem to have in your case ;-)

        Doctors are in the business of healing (ethical doctors anyway) so they'll use what has been shown to work. And psychology is an art not a science - while training has become more rigorous, most psychologists aren't trained medical doctors. They're trained in the art of analysis and talk therapy, which isn't a science even if scientific methodologies are applied to it.

        Glad to hear you also found something that worked for you, and are at a point where you have resolved some of the issues surrounding the depression and can now manage without drugs :-)
      • Re: Post Traumatic Stress Disorder

        Wed, November 21, 2007 - 5:58 AM
        Kai - And, yes, the new drugs sound promising but from my understanding it's still all pretty hypothetical at this point and a lot of things which sound good in the lab don't bear fruit when applied to humans. Though certainly a lot more is understood about PTSD than even a couple of years ago - there's been a lot of interesting research coming out (which no doubt contributes to the current trendiness of this diagnosis). With the amount of soldiers returning from Iraq with PTSD mounting, it's only going to get more press over the next couple of years. It will be interesting to see if anyone tackles this in the context of brain differences between men and women since there are some quite critical differences around emotional responses and memory formation regarding trauma between the sexes.
        • Re: Post Traumatic Stress Disorder

          Wed, November 21, 2007 - 11:02 AM
          "It will be interesting to see if anyone tackles this in the context of brain differences between men and women since there are some quite critical differences around emotional responses and memory formation regarding trauma between the sexes."

          I assume you mean "brain differences between the sexes" and not "trauma between the sexes"? (Though of course the latter exists, viz. my own experiences. =;/ ) Ambiguous syntax/punctuation...

          That's of personal interest to me because of a dear friend and former housemate in SF of mine, a woman who's the president of her own web redesign consulting company. Very, very competent, a speaker in demand, etc., but occasionally she had to withdraw from social interaction beause of what she described as PTSD, caused, I think, by a physically abusive ex-husband. (She wouldn't talk about it, but there were indirect hints.) I'd like to see this impediment to her greater fulfillment removed.

          Have you followed the Doonesbury cartoon thread this year about a woman Iraq vet who's being counselled for PTSD and depression from being raped by a fellow soldier? Pretty heavy and heady stuff even for Garry Trudeau. He seems righteously aware of this aspect of psychological blowback from the imperium's misadventures...
          • Re: Post Traumatic Stress Disorder

            Wed, November 21, 2007 - 1:43 PM
            Kai - Um, I meant that the way male and female brains respond to trauma is different, as well as the duration of trauma after the event. This would indicate that memory formation regarding trauma is also different in male and female brains.

            Vis a vis your friend. I've generally found that keeping traumatic events secret magnifies them. One of the reason talk therapy helps one integrate (not "get over" but integrate) traumatic events is that the "shameful secret" is shared and is no longer a secret and eventually no longer shameful. Sounds like you're friend has a bit of a disconnect with herself going on - an sort of strong and perfected image she presents to the outside world while her inner experience of herself is perhaps quite different. This isn't that uncommon in highly successful women who are attracted to abusive men. Not knowing your friend, I could of course be totally off the mark here so I'm just offering up this as a suggestion :-)

            I haven't read Doonesbury for a while, sounds like it would be worth checking out. The US is in for a world of hurt when all their children come home from war.
            • Re: Post Traumatic Stress Disorder

              Wed, November 21, 2007 - 1:52 PM
              Kai - And by trauma I mean emotional and psychological trauma and extreme stress, not physical trauma. I suspect that the effect of hitting either a man or the woman on the head in a way that causes physical trauma would be pretty much the same! Ouch ;-)
            • Re: Post Traumatic Stress Disorder

              Thu, November 22, 2007 - 2:40 PM
              Actually you were off the mark, but then it's a case of insufficient data to compute. -) She didn't talk about it with *me*, we were only housemates my last year in SF, but she certainly did with oldest/deepest friends, I think, and I'm sure that despite the times she'd feel the need to escape from social contact (I remember once dropping her off in my van near that Presidio reclaimed marsh area, at her request, so she could go decompress or whatever for the afternoon; sometimes being a friend just means helping however one is asked to and not probing as to why the particular request), she wasn't suppressing anything out of shame. When someone who is generally very empathetic and wise shows signs of a trauma they don't want to share with even relatively inner circles, It's best to take them at their word and try not to jump to any conclusions. All I know is what she directly told me and other friends.

              So while I know for a fact that her ex was abusive, I refrain from assuming she was attracted to that sort, or or anything like that, or that she has an inner/outer disconnect, or wasn't in a process of integrating. The most I'd say would be that she was justly proud of her work and had a lot of pressure in being responsible for a half dozen people (Web companies even in the late 90s-early-00's were fragile entities) while at the same time dealing with the fallout from the divorce as well as the PTSD but probably thinking "I can't spend too much time on this, people are depending on me." And as you know, that pressure is automatically more severe, and the price of failure greater, for a woman in an executive role, especially in the tech biz, which has some major bias-denial syndromes. (I'll refrain my my usual rant and just say go read Cyberseifish, by my e-pal Paulina Borsook.)

              Maybe PTSD is different neurologically for women, certainly it must be different sociologically.
              • Re: Post Traumatic Stress Disorder

                Fri, November 23, 2007 - 8:44 AM
                Hey, I could only go by the info you gave me :-) No need to go into the details of this person's life! Not like it's going to help us or her, I just brought it up because you'd said she had PTSD (but on further explanation it sounds even less like she has PTSD).
                • Re: Post Traumatic Stress Disorder

                  Fri, November 23, 2007 - 9:49 AM
                  I find it hard to believe this problem (PTSD) can be cured overnight. It seems to be trauma goes deep and it takes time to unwind what has been wound.
                  • This is the maximum depth. Additional responses will not be threaded.

                    Re: Post Traumatic Stress Disorder

                    Fri, November 23, 2007 - 10:16 AM
                    Robert - Well PTSD actually occurs in an instant and has specific neurobiological markers (though most diagnosis is made on the basis of symptoms, not a physical test). Whether the fact that it occurs in an instant means it can be cured overnight is another thing. It should also be noted that it's starting to look like there has to be a predisposition for PTSD for it to occur - as well as the incomprehensible horrific/traumatic event. Most treatments focus on management and desensitization (which seems to be true for EMDR). PTSD is a specific disorder, so what may "seem" true for one type of emotional trauma may well be different for another form of trauma. Perhaps you can present some evidence to support your belief? :-)
                • Re: Post Traumatic Stress Disorder

                  Fri, November 23, 2007 - 11:56 AM
                  "Hey, I could only go by the info you gave me" -

                  Yeah, like I said - insufficient data (for you) to compute. But I take her at her word about her having PTSD. She did mention it, and doctor visits, several times. No reason to doubt it, based on everything else I know of and from her.

                  I find it useful to ponder her situation especially because of how high-functioning she is despite it, just as some of us can manage, with some not inconsiderable effort, most of the time (interspersed with occasional spectacular plunges, however) with other cognitive disabilities; in my own case, depression.
                  • This is the maximum depth. Additional responses will not be threaded.

                    Re: Post Traumatic Stress Disorder

                    Sun, December 23, 2007 - 7:17 PM
                    I've been involved in several different types of therapy throughout the past 20 years all aimed at alleviating some of the more dysfunctional aspects of my PTSD. Some seemed to work after a few months, but required that I remain in that particular type of therapy, and on psychotropics, for the rest of my life in order to facilitate daily functioning for the rest of my life. Those included behavioral and cognitive therapy along with a cocktail of anti-anxiety meds...some for the immediate anxiety and others for the long term prevention.

                    Others didn't seem to work at all. Psychotherapy, for example, seemed to exacerbate it.

                    When I stumbled upon EMDR I was highly suspicious. I'd been in state of near agoraphobia for about 3 months and the main reason I chose THIS therapist was because her office was 3 blocks from my house, and I could walk there by taking a back alley thereby avoiding all the places that triggered my anxiety. Within 4 sessions I was able to leave the house for other necessary errands! I still couldn't go to certain places, but I was at least able to function beyond my home to some degree. I was able to work again! (And this was of primary concern because we were facing an eviction notice due to my previous inability to go just about anywhere).

                    The part that I was both most suspicious of and most relived by was that this form of therapy didn't require my "talking" about the experiences that led to my PTSD. I was asked to assign it a number, ask my physical body where it was experiencing the stress and what form or shape it took, then I was given the task of rationalizing it silently--which of course brought up all sorts of emotions, but I was never asked to express them verbally.

                    Throughout all of this I held onto these little buzzy thing's in my palms that I basically forgot about. It was almost hypnotic, but I was consciously right there every step of the way. As we metaphorically walked away from the source of the stress, I was periodically asked to assign a new number and reach inside my body to determine where and what shape it was taking. Then we 'closed' by finding a safe place and a lock box of some sort to place the stressors in til the next time, and we turned off the little buzzy things.

                    All I know is that after more than 20 years of dealing with PTSD, and I was a high functioning case for about 10 of those years (not all together), I saw a light at the end of the tunnel. I actually saw a way OUT that didn't include weekly therapy and daily medication and it was as if I could finally BREATHE again.

                    I haven't been in any sort of therapy for the past few months (insurance issues) and while I still feel like I'd benefit from more EMDR, I'm nowhere close to the mess I was before it! It saved my life...and my livelihood and therefor my kiddo's lives. The fact that it worked so immediately, didn't require continual drug therapy and gave me the ability to see a life BEYOND this mess is worth every minute and dollar I put into it.

                    -K

  • Re: Post Traumatic Stress Disorder

    Mon, December 24, 2007 - 11:37 AM
    Here's an out of the box view www.maps.org/pipermail/m.../000004.html - but it is well know in the "community" how effective plant entheogens are regarding PTSD. If one were truly concerned with healing, overlooking our unfortunate prejudice regarding these substances, here you go. For some of us it is just so sad to see anyone, but especially so many of our soldiers, suffering essentially needlessly as the answer grows naturally out the ground, in most instances effective with no refinement whatsoever.